Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9092 | 9092-30827 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | K43T, F53FL | L10I, K20R, E35D, M36I, R41K, K55KR, R57K, Q61D, I62V, L63T, E65ED, I72T, T74TS, L89M |
| >9092-30827| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWTPKIIGGIGGLVRVKQYDDVT IDICGHKATGSVLVGPTPANIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | K43N, K49R, E53D, V118VI, K122E, I135V, S162H, K166Q, E169D, K173A, Q174K, D177E, I178L, E194ED, T200A, Q207E, H208Y, R211K, W212M, L228H, Q242H, V245Q |
| >9092-30827| codons 38-247 CTELENEGKISRIGPDNPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQHSMTQILDPFRAKNPELVIYQYMDDLYVGSDLDIGQHRAKIEELREYLLKMGFYTP DKKHQKEPPFHWMGYELHPDKWTVHPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |