<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9092 9092-30827 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M K43T, F53FL L10I, K20R, E35D, M36I, R41K, K55KR, R57K, Q61D, I62V, L63T, E65ED, I72T, T74TS, L89M  
>9092-30827| codons 4-99
TLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWTPKIIGGIGGLVRVKQYDDVT
IDICGHKATGSVLVGPTPANIIGRNMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T215Y       K43N, K49R, E53D, V118VI, K122E, I135V, S162H, K166Q, E169D, K173A, Q174K, D177E, I178L, E194ED, T200A, Q207E, H208Y, R211K, W212M, L228H, Q242H, V245Q  
>9092-30827| codons 38-247
CTELENEGKISRIGPDNPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQHSMTQILDPFRAKNPELVIYQYMDDLYVGSDLDIGQHRAKIEELREYLLKMGFYTP
DKKHQKEPPFHWMGYELHPDKWTVHPIQLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006