Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9094 | 9094-30827 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, L74I, M184V, L210W, T215Y | K219N | Y181C | V108VI, V179D, F227L | E44D, K103R, V106VI, V111I, K122A, I135T, S162C, M164ML, R172RK, K173A, Q174K, D177EG, I178L, E203D, Q207D, R211K, H221Y, V245Q |
| >9094-30827| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKRKSITILDIGDAYFSVPLDADFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSLTKILEPFKAKNPGLDICQYVDDLYVGSDLEIGQHRTKIDELRDHLWKWGFYTP DNKYQKEPPLLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54V, V82A | L24LI, L33F, Q58E | L10I, I15V, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P |
| >9094-30827| codons 4-99 TLWQRPIVTIKVGGQLKEALIDTGADDTIFEDINLPGKWKPKIVGGIGGFVRVKEYENIP IEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |