<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9094 9094-30827 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54V, V82A L24LI, L33F, Q58E L10I, I15V, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P  
>9094-30827| codons 4-99
TLWQRPIVTIKVGGQLKEALIDTGADDTIFEDINLPGKWKPKIVGGIGGFVRVKEYENIP
IEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, L74I, M184V, L210W, T215Y K219N Y181C V108VI, V179D, F227L E44D, K103R, V106VI, V111I, K122A, I135T, S162C, M164ML, R172RK, K173A, Q174K, D177EG, I178L, E203D, Q207D, R211K, H221Y, V245Q  
>9094-30827| codons 38-247
CTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHP
AGLKKRKSITILDIGDAYFSVPLDADFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQCSLTKILEPFKAKNPGLDICQYVDDLYVGSDLEIGQHRTKIDELRDHLWKWGFYTP
DNKYQKEPPLLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006