<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9091 9091-30827 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M V11I, L33F, Q58E, G73S, L89V L10I, I13V, L24F, N37D, K55R, D60DN, I62V, L63P, K70KN, A71I, I72M, V77I, C95L  
>9091-30827| codons 4-99
TLWQRPIITVKIGGQLKEALFDTGADDTVFEEMDLPGRWKPKLIGGIGGFVRVREYNQVP
IEICGHNIMSTVLIGPTPANIIGRNVMTQIGLTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, Q151M, M184V, T215FV F116Y, K219Q K101E, Y181C, G190A V108VI T39A, V60I, T69N, K122E, D123N, I135T, S162SC, I167V, D177E, I178L, V179I, G196E, H208Y, D218E, L228HQ, V245IM  
>9091-30827| codons 38-247
CAELEKEGKISKIGPENPYNTPIFAIKKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTILDVGDAYYSVPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQCSMTKVLEPFRKQNPELIICQYVDDLYVASDLEIEQHRTKIEELRQYLLRWGFVTP
EQKHQKEPPFQWMGYELHPDKWTVQPIMLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006