Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9328 | 9328-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, L74I, V75T, L210W, T215Y | K219Q | Y181C | V108I | T39TA, E44D, A98S, K101R, K104N, V118I, K122E, S162D, K166R, V179VI, D192DN, T200A, E203K, Q207E, R211K, D218E, L228H |
| >9328-30930| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGIPHP SGLRKKNSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQDSMTRILEPFRKQNPDIIICQYMDDLYVGSNLEIGQHRAKIKELREHLWKWGFYTP EQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54L, V82A, L90M | F53L, Q58E | K20R, E35D, M36I, N37D, R41RK, K55R, D60E, I62IV, L63P, A71V, I93L |
| >9328-30930| codons 6-99 WQRPLVTIKIGGQLREALLDTGADDTVLEDIDLPGKWKPKIVGGIGGLLRVREYEQVPIE ICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |