<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9328 9328-30930 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54L, V82A, L90M F53L, Q58E K20R, E35D, M36I, N37D, R41RK, K55R, D60E, I62IV, L63P, A71V, I93L  
>9328-30930| codons 6-99
WQRPLVTIKIGGQLREALLDTGADDTVLEDIDLPGKWKPKIVGGIGGLLRVREYEQVPIE
ICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, L74I, V75T, L210W, T215Y K219Q Y181C V108I T39TA, E44D, A98S, K101R, K104N, V118I, K122E, S162D, K166R, V179VI, D192DN, T200A, E203K, Q207E, R211K, D218E, L228H  
>9328-30930| codons 38-247
CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGIPHP
SGLRKKNSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQDSMTRILEPFRKQNPDIIICQYMDDLYVGSNLEIGQHRAKIKELREHLWKWGFYTP
EQKHQKEPPFHWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006