Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9326 | 9326-30929 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L10F, L24I | I15V, E35D, N37T, R57K, D60E, I62V, L63P, I64V, A71V, I72IV, I93L |
| >9326-30929| codons 4-99 TLWQRPFVTIKVGGQLKEALIDTGADDTVLEDMTLPGRWKPKIIGGIGGFVKVKQYEQVP VEICGHKVVGTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K101E, G190S | A98G | V60VI, S68G, K122E, D123N, I135T, E138A, V189VI, T200A, E204D, Q207A, V245T |
| >9326-30929| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLEKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYISSDLEIGQHRAKIEDLRAHLLRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |