Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9321 | 9321-30924 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | Y188L | V60VI, K122E, T139TA, S162Y, Q174K, N175Y, Q207E, R211K |
| >9321-30924| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKKYPDIVIYQYMDDLLVGSDLEIGQHRTKIEELREHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54V, V82A, L90M | L33LF, G73T | L10I, N37D, I62V, L63P, A71I, V77I, I93L |
| >9321-30924| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMDLPGRWKPKIIGGIGGFVKVRQYDQVP IEICGHKIITTVLIGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |