Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9314 | 9314-30922 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, M184MV | K219Q | K101KE, K103KN, V106IM, Y181I, M230ML | K43R, V118I, K122E, D123N, I135T, E138EA, Q174R, V179VG, T200A, I202V, F214L, H221Y, K238R, V245T | Y232H |
| >9314-30922| codons 38-247 CTEMEREGKISKIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKNKSMTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPDIGIIQYVDDLYVGSDLEIGQHRAKVEELRQHLLRWGLTTP DQKYQKEPPFLWLGHELHPDRWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L23I, Q58E | L10V, L19I, E35D, M36I, N37S, R41K, I62V, L63P, A71V, I72IV, I93L | R8Q |
| >9314-30922| codons 4-99 TLWQQPVVTIKIGGQIKEAILDTGADDTVLEDISLPGKWKPKLIGGIGGFVKVREYDQVP IEICGHKVVGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |