Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9232 | 9232-30916 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V, T215F | D67G, K219E | Y181C, G190A | S68G, I135T, I142V, K166R, Q174R, V179I, R211K, D218E, L228H, V245E |
| >9232-30916| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKGGTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKRNPDIIICQYVDDLYVASDLEIGQHRTKIEELRQHLLKWGFFTP EEKHQKEPPFHWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | G73S | L10V, I15V, K20T, N37D, L63P, A71V, V77I, I93L |
| >9232-30916| codons 4-99 TLWQRPVVTIKVGGQLTEALLDTGADDTVLEEMDLPGRWKPKIIGGIGGFIKVRQYDQIP IEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |