Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9017 | 9017-30909 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215TFIS | K219Q | K101KE, G190A | I142IV, S162A, V179I, F214FL, V245E |
| >9017-30909| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPDIIIYQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGLSTP DQKHQKEPPFLWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46ML, I47V, I54M, V82A | L10F, L33F, L89V | K20KR, M36I, L63P, A71V |
| >9017-30909| codons 4-99 TLWQRPFVTIKIGGQLREALLDTGADDTIFEEINLPGRWKPKLVGGIGGFMKVRQYDQIP IEICGHKVIGTVLVGPTPANIIGRNVLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |