Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9020 | 9020-30909 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69DN, K70KR | Y181C | V90I, K102Q, S162C, T165I, D177E, T200A, I202V, E203K, R211K, K223Q, L228R | G152GE |
| >9020-30909| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSNRWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQEWKGSP AIFQCSMIKILEPFRKQNPEIVICQYMDDLYVGSDLEIGQHRAKVKELRQHLLKWGFTTP DKKHQQEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, G17E, M36MI, I62V, L63P, A71T, I93L |
| >9020-30909| codons 4-99 TLWQRPIVTVKIGEQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQVP IEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |