Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9013 | 9013-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K101KE, K103KNRS, G190GA | K65KE, A98S, K122KE, D123E, I135T, E138A, Q174R, L187LS, G196GR, Q197E, R211K, P243H, I244IM, V245E |
| >9013-30908| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKEKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLEKSKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPDIVIYQYVDDSYVASDLEIREHRTKIEELRQHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQHMELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, L76LV, V82A, L90LM | L33F | L10IV, G16E, L19LV, N37D, R41K, I62IV, L63HP, I72V |
| >9013-30908| codons 4-99 TLWQRPVVTIKIEGQVKEALLDTGADDTVFEEMDLPGKWKPKLIGGIGGFVKVRQYDQVP IEICGHKAVGTVVVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |