<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9014 9014-30908 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70E, Q151M V75T, F77L, F116Y K101E, Y181C, G190A   T58N, V60I, K73M, D121H, K122E, I135T, T139A, Y146H, I178M, F214L, H221Y, V245N  
>9014-30908| codons 38-247
CTEMEKEGKISKIGPENPYNNPIFAIKKKNSTEWRMLTDLRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTVLDVGDAYYSVPLHEDFRKYTAFTIPSTNNEAPGIRYQHNVLPMGWKGSP
AIFQSSMTKILEPFRKQNPDMVICQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGLTTP
DKKYQKEPPFLWMGYELHPDKWTVQPINLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82A, L90M G73S L10I, E35D, M36I, N37D, I62V, L63P, A71V, I72L  
>9014-30908| codons 4-99
TLWQRPIVTIKIGGQLKEALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVRQYDQVP
IEICGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006