Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9293 | 9293-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75M, L210W, T215Y | K103KN, G190GACS | T39A, K43N, K49R, K101Q, K122E, D123DG, I135T, R211K, L228R |
| >9293-30930| codons 38-247 CAELENEGKISRIGPENPYNTPVFAIKKKDSTKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLQKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVSSDLEIGQHRTKIEELRQHLWKWGFYTP DKKHQKEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, V82M, L90M | L33F, K43T | L10V, K20R, E35D, M36I, N37D, L63P, A71V, I93L |
| >9293-30930| codons 4-99 TLWQRPVVTIKIGGQLREALLDTGADDTVFEDIDLPGRWTPKMIGGIGGFMKVRQYDQIP IEICGHKVIGTVLVGPTPMNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |