<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9294 9294-30930 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, V82A L24I L10I, I15IV, E35D, M36I, N37ND, R41K, I62V, L63P, T74S  
>9294-30930| codons 4-99
TLWQRPIVTIKVGGQLKEALIDTGADDTVLEDIDLPGKWKPKIIGGIGGFIKVRQYDQVP
IEICGHKAIGSVLVGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, V75T, M184V, L210W, T215F K219Q Y181C, G190A K101H, V108VI T69N, V118VI, K122E, S162D, R211RK, D218E, V245K  
>9294-30930| codons 38-247
CTELEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKITDFRELNKRTQDFWEVQLGIPHP
AGLHKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRTKIEELRQHLWKWGFFTP
EQKHQKEPPFLWMGYELHPDKWTVQPIKLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006