<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9281 9281-30925 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, M184MV, L210W, T215Y K219KR Y181V, G190A A98G, K101HQ, V108VI, F227L K43E, E44A, V118I, K122E, D123DN, I135T, S162D, S163G, K166KR, V179VI, G196E, T200TIM, E203K, R211K, H221HY, K223Q, L228H, V245M P140T
>9281-30925| codons 38-247
CTELEEAGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGLQKKKSVTILDVGDAYFSIPLDENFRKYTAFTIPSTNNETTGIRYQYNVLPQGWKGSP
AIFQDGMTRILEPFRKQNPDIIIVQYVDDLYVASDLEIEQHRMKIKELRQHLWKWGFYTP
DRKYQQEPPLHWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L10F, V11I, G73S T12S, K14N, I15V, L19Q, K20V, M36I, K55R, R57K, I62V, L63P, A71V, I72L, N83S, I85V  
>9281-30925| codons 4-99
TLWQRPFISINVGGQQVEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVRVKQYDQVP
IEICGHKVLSTVLVGPTPVSVVGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006