Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9263 | 9263-30923 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | Y188L, G190GA | K101H | K43Q, V60VI, V118VI, K122E, S162C, R172RK, D177E, V179I, R211K, L228H |
| >9263-30923| codons 38-247 CTELEQEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLHKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFKKQNPEIIIYQYMDDLLVASDLEIGQHRTKIEELRQHLWKWGFYTP DKKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, L33F, G73T | L19I, K55R, R57K, I62IV, L63Q, I64V, I66V, C67F, H69CR, I72V, V77I, I93L |
| >9263-30923| codons 4-99 TLWQRPFVTIKIGGQIKEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFVRVKQYDQVQ VEVFGRKAVTTVLIGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |