Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9264 | 9264-30923 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215FY | K101P, K103S | K43E, E44EA, V60VI, V118I, K122P, D123E, I135IT, S162SDGN, I178L, V179I, G196GE, Q197K, V245M |
| >9264-30923| codons 38-247 CTELEEAGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLPKSKSVTVLDVGDAYFSIPLDPEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPDLIIYQYMDDLYVGSDLEIEKHRTKIEELRQHLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47A, V82A | L10I, L63P, A71T, V77I, I93L |
| >9264-30923| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIAGGIGGFIKVRQYDQIP IEICGHKTIGTVLIGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |