Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9262 | 9262-30922 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47IV, I54V, L90M | G73T | L10R, I13M, K14R, L19I, K20I, E35D, M36I, I62V, L63P, I64V, I93L, C95F |
| >9262-30922| codons 4-99 TLWQRPRVTMRIGGQIIEALLDTGADDTVLEDINLPGRWKPKIVGGIGGFVKVRQYDQVP VEICGHKAITTVLVGPTPVNIIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70R | K219Q | Y181C, G190GA | V90VI, D121Y, K122E, I135T, V179VI, I202V, R211K, F214L, L228LR |
| >9262-30922| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLYEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIICQYMDDLYVASDLEIGQHRTKVEELRQHLLKWGLTTP DQKHQKEPPFRWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |