Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9079 | 9079-30903 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70KR, L74IV, V75M, M184MV, T215F | D67G, K219Q | L100I, K103N | T39A, K43E, T69N, L109LP, D123E, I135T, D177E, G196E, I202V, D218E, L228H, P243T | S68SDGN |
| >9079-30903| codons 38-247 CAELEEEGKISKIGPENPYNTPVFAIKKKGNNRWRKVMDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVPDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIEQHRTKVEELRQHLLRWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQTIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, I84V, L90M | L10F, G73T | Q18H, K20I, E34Q, M36I, N37ND, R41K, G51A, K55R, D60E, L63P, I64V, A71V, P79AD, I85V |
| >9079-30903| codons 4-99 TLWQRPFVTIKIGGHLIEALLDTGADDTVLQEIDLPGKWKPKIIGGIAGFMRVRQYEQIP VEICGHKVITTVLVGDTPVNVVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |