Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9080 | 9080-30903 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I50V, I54V, V82A | L33F, K43IT | L10I, K20R, E35D, M36I, N37D, I62V, L63P, I64V, L89LIM |
| >9080-30903| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVFEDIDLPGRWTPKMIVGVGGFVKVRQYDQVP VEICGHKAIGTVLVGPTPANIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, L210W, T215Y | K219R | K103N, G190A | V108I | K43E, E44A, V90I, V118I, K122E, R172RK, I178M, T200K, E203D, R211K, H221Y, V245R |
| >9080-30903| codons 38-247 CTELEEAGKISKIGPENPYNTPVFAIKKKNSDKWRKLMDFRELNKRTQDFWEIQLGIPHP AGLKKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFKKQNPDMVIYQYMDDLYVASDLEIGQHRKKIDELRQHLWKWGFYTP DRKYQKEPPFLWMGYELHPDKWTVQPIRLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |