Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9075 | 9075-30902 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, V82A, L90M | K43T | L10I, I15IV, G16A, K20R, E35D, M36I, N37D, K55KR, R57RK, D60E, I62V, L63P, A71V, I72T, I93L |
| >9075-30902| codons 4-99 TLWQRPIVTIKVAGQLREALLDTGADDTVLEDIDLPGRWTPKIIGGIGGFVRVKQYEQVP IEICGHKVTGTVVVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74LI, M184V, L210LW, T215Y | V75VALS | T39TA, K43E, E44A, S48T, S68SG, V118VI, K122E, D123DN, I142IV, S162SDGN, K166R, V179VI, E203ED, H208HY, R211K | H221HCRY |
| >9075-30902| codons 38-247 CAELEEAGKITKIGPENPYNTPVFAIKKKDGTKWRKISDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQNSMTRILEPFRKQNPDIIIYQYVDDLYVGSDLEIGQHRTKIDELRQYLWKWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |