<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9076 9076-30902 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82S, L90M K43T L10V, K20R, E35D, M36I, I62V, L63P, A71V, T74S, I93L  
>9076-30902| codons 4-99
TLWQRPVVTIKIGGQLREALLDTGADDTVLEDINLPGRWTPKMIVGIGGFVKVRQYDQVP
IEICGHKVIGSVLVGPTPSNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184MV, L210W, T215Y K219N K103N, M230L L234I T39A, K43E, E44A, K64H, V106I, V111I, V118I, D121DH, K122E, S162D, G196E, T200A, H208HY, R211K, L228H, V245R  
>9076-30902| codons 38-247
CAELEEAGKISKIGPENPYNTPVFAIHKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSITVLDIGDAYFSIPLHEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRAKIEELRQYLWKWGFYTP
DNKHQKEPPFHWLGYEIHPDKWTVQPIRLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006