Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9073 | 9073-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70KR, V75IT, L210W, T215F | K219Q | L100I, K103N | A98G | V60I, V118I, D123E, I135T, Q174R, D177E, I202V, E203A, Q207E, R211K, L228H |
| >9073-30901| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKLTDFRELNKRTQDFWEVQLGIPHP GGIKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPEIVIYQYMDDLYVGSDLEIGQHRTKVAELREHLWKWGFFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L90M | Q58E | L10V, T12P, L19I, K20I, M36I, L63P, A71V, V77I, V82I, I85V, Q92K, I93L |
| >9073-30901| codons 4-99 TLWQRPVVPIKIGGQIIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVREYDQIP IEICGHKVIGTVLIGPTPINIVGRNLMTKLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |