<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9073 9073-30901 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70KR, L210W, T215F V75IT, K219Q L100I, K103N A98G V60I, V118I, D123E, I135T, Q174R, D177E, I202V, E203A, Q207E, R211K, L228H  
>9073-30901| codons 38-247
CTELEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKLTDFRELNKRTQDFWEVQLGIPHP
GGIKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKRNPEIVIYQYMDDLYVGSDLEIGQHRTKVAELREHLWKWGFFTP
DQKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L90M Q58E L10V, T12P, L19I, K20I, M36I, L63P, A71V, V77I, V82I, I85V, Q92K, I93L  
>9073-30901| codons 4-99
TLWQRPVVPIKIGGQIIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVREYDQIP
IEICGHKVIGTVLIGPTPINIVGRNLMTKLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006