Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9341 | 9341-30930 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I, L33F | L10I, I13IV, I62IV, L63D, E65D, A71V, I72K, V77I |
| >9341-30930| codons 4-99 TLWQRPIVTVKIGGQLKEALIDTGADDTVFEEMNLPGRWKPKLIGGIGGFVKVRQYDQVD IDICGHKVKGTVLIGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219KE | D121H, K122E, I135T, I142V, K166R, D177E, G196E, T200A, E203K, Q207E |
| >9341-30930| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPEIVIYQYVDDLYVGSDLEIEQHRAKIKELREHLLRWGFTTP DEKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |