Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9302 | 9302-30918 | Brazil | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, M184V, T215F | K219Q | K103N | K238N | T39D, V60VI, K122E, D123S, I135T, K173A, D177E, T200A, I202V, Q207E, R211K, V245Q |
| >9302-30918| codons 38-247 CDELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFFTP DQKHQKEPPFLWMGYELHPDNWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10F, G73GS, L89IMV | I15V, K20I, E35D, M36I, N37K, R41N, Q61H, L63P, H69K, A71V, I85V, I93L |
| >9302-30918| codons 4-99 TLWQRPFVTIKVGGQLIEALLDTGADDTVLEDIKLPGNWKPKMIGGIGGFVKVRQYDHIP IEICGKKVISTVLVGPTPANIVGRNVMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |