<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9300 9300-30917 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, M184V, L210W, T215Y V75A, K219E K103N V108I E40F, K43E, V118I, K122E, D123E, S162Y, H208Y, R211RK, K223Q, L228H, Q242H, V245M L92LIM
>9300-30917| codons 38-247
CTFLEEEGKISKIGPENPYNTPVFAIKKKNSTKWRKIADFRELNKRTQDFWEVQMGIPHP
AGLKKNKSVTILDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTP
DEKHQQEPPFHWMGYELHPDKWTVHPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82VF, L90M F53FL, G73C L10I, L19LI, K20R, E35D, M36I, R57K, I62V, L63P, I64V, A71V, I72V  
>9300-30917| codons 4-99
TLWQRPIVTIKIGGQIREALLDTGADDTVLEDINLPGRWKPKMIGGIGGLVKVKQYDQVP
VEICGHKVVCTVLVGPTPFNIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006