Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9300 | 9300-30917 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82VF, L90M | F53FL, G73C | L10I, L19LI, K20R, E35D, M36I, R57K, I62V, L63P, I64V, A71V, I72V |
| >9300-30917| codons 4-99 TLWQRPIVTIKIGGQIREALLDTGADDTVLEDINLPGRWKPKMIGGIGGLVKVKQYDQVP VEICGHKVVCTVLVGPTPFNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, M184V, L210W, T215Y | V75A, K219E | K103N | V108I | E40F, K43E, V118I, K122E, D123E, S162Y, H208Y, R211RK, K223Q, L228H, Q242H, V245M | L92LIM |
| >9300-30917| codons 38-247 CTFLEEEGKISKIGPENPYNTPVFAIKKKNSTKWRKIADFRELNKRTQDFWEVQMGIPHP AGLKKNKSVTILDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTP DEKHQQEPPFHWMGYELHPDKWTVHPIMLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |