Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9297 | 9297-30916 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K219R | V106A, G190A | F227L | K43Q, E44D, K101Q, S105T, V118I, K122E, R172K, H208Y, H221Y, K223Q |
| >9297-30916| codons 38-247 CTELEQDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLQKKKTATVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFKKQNPDIVIYQYVDDLYVASDLEIGQHRTKIEELRQYLWRWGFYTP DRKYQQEPPLLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47IV, I54V, V82ST, L90M | L10F, K43KT, G73S | I15V, K20I, E35D, M36I, I62V, L63P, A71V, I85V |
| >9297-30916| codons 4-99 TLWQRPFVTIKVGGQLIEALLDTGADDTVLEDINLPGRWTPKIVGGIGGFVKVRQYDQVP IEICGHKVISTVLVGPTPTNIVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |