<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9298 9298-30916 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, V75VIM, M184V, L210W, T215Y K219N K101E, Y181C, G190S   T39TA, K43E, E44A, A98S, L109I, V118I, K122E, I135T, S162CY, V179I, Q207E, H208Y, R211K, D218E, L228H  
>9298-30916| codons 38-247
CAELEEAGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP
SGLEKKKSVTVIDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRKQNPDIIICQYVDDLYVSSDLEIGQHRTKIEELREYLWKWGFYTP
ENKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82S, L90M K43T, G73GS L10I, I13V, K20I, E34EQ, E35D, M36I, I62V, L63P, A71V, T74S  
>9298-30916| codons 4-99
TLWQRPIVTVKIGGQLIEALLDTGADDTVLQDINLPGRWTPKMIVGIGGFVKVRQYDQVP
IEICGHKVISSVLVGPTPSNIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006