Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9203 | 9203-30916 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L24I, L33F, G73S | W6WL, L10V, G16GA, E35D, M36IL, N37DE, K55R, I62V, L63P, A71V, I72IMT, I93L |
| >9203-30916| codons 4-99 TLLQRPVVTIKIAGQLKEALIDTGADDTVFEDLELPGRWKPKIIGGIGGFVRVRQYDQVP IEICGHKVTSTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M, M184V | A62V, V75I, F77L, F116Y | S68G, T69X, D123E, I178IM, H208HY |
| >9203-30916| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDGXKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAFYSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |