Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9200 | 9200-30911 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML, V82A, L90M | L10IV, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I93L |
| >9200-30911| codons 4-99 TLWQRPVVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKLIGGIGGFIKVKQYDNIP IEICGHKAIGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | K101P, K103N | K49R, K64R, K104KR, K122KE, I135V, S162Y, K166KE, K173A, Q174K, D177E, V179VI, T200A, R211K, V245Q |
| >9200-30911| codons 38-247 CTEMEKEGKISRIGPENPYNTPVFAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLPKNRSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQYSMTEILEPFRAKNPEIIIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |