Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9198 | 9198-30910 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82AS | L24I, L33LF, F53FL, Q58QE | L10I, K20R, E35D, M36I, R41K, D60E, L63P, I64V, A71V, I93L |
| >9198-30910| codons 4-99 TLWQRPIVTIKIGGQLREALIDTGADDTVFEDINLPGKWKPKMIGGIGGLVKVREYEQIP VEICGHKVIGTVLVGPTPSNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70R, M184V | D67G, K219Q | E42EG, T69Y, K122E, D123E, T200V, Q207A, R211K, V245K |
| >9198-30910| codons 38-247 CTELGKEGKISKIGPENPYNTPVFAIKKKGSYRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRVKIEELRAHLLKWGFTTP DQKHQKEPPFLWMGYELHPDKWTVQPIKLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |