Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9197 | 9197-30910 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | A62V | V118I, K122E, I135T, K173R, V179I, R211S, F214L, Q242H, P243H, L246M | F171FV |
| >9197-30910| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPVRRQNPDIIIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLSWGLFTP DKKHQKEPPFLWMGYELHPDKWTVHHIVMP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L24I | L10I, T12P, K14GR, K55R, R57K, L63P, G68D, A71V, I93L |
| >9197-30910| codons 4-99 TLWQRPIVPIRIGGQLKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFVRVKQYDQIP IEICDHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |