Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9194 | 9194-30903 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219R | V108VI | T39A, E44D, W88WC, K104N, V118I, K122E, S162D, D192Y, E203D, Q207E, H208Y, R211K, H221Y |
| >9194-30903| codons 38-240 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFCEVQLGIPHP AGLKKKNSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFRKQNPDIVIYQYMDDLYVGSYLEIGQHRTKIDELREYLWKWGFYTP DRKYQKEPPFLWMGYELHPDKWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, L33LF, G73S | K20KR, E35D, M36I, I62V, L63P, A71V, I93L |
| >9194-30903| codons 4-99 TLWQRPFVTIKIGGQLREALLDTGADDTVFEDINLPGRWKPKIIGGIGGFVKVRQYDQVP IEICGHKVISTVLVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |