Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9193 | 9193-30903 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74V, M184V, L210W, T215Y | K219E | L100I, K103N | T39A, E44D, V118I, K122E, D177G, H208Y, R211K, D218E, L228H |
| >9193-30903| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPGIVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTP EEKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, I84V, L90M | L10F, V11I, G73ST | T12TP, I13V, I15V, K20I, M36I, I62V, L63P, C67F, A71V, P79A, I93L |
| >9193-30903| codons 4-99 TLWQRPFIPVKVGGQLIEALLDTGADDTVLEEINLPGRWKPKIVGGIGGFVKVRQYDQVP IEIFGHKVITTVLVGATPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |