<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9355 9355-30925 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   K20I, M36I, I62V, L63LP, I64V, T74TS  
>9355-30925| codons 4-99
TLWQRPLVTIKIGGQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQVP
VEICGHKAIGSVLVGPTPVNIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, L210W, T215Y D67DEG, V75VM, K219N K101E, K103N, Y181C, G190A   K65KE, S68G, K73KM, K104KQ, K122E, E169D, R172RK, D177E, I178L, T200A, R211K, V245E N57NH, H235HR
>9355-30925| codons 38-247
CTELEKEGKISKIGPENPYHTPVFAIKEKGGTKWRMLMDFRELNKRTQDFWEVQLGIPHP
AGLEKNQSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILDPFKKQNPELVICQYMDDLYVASDLEIGQHRAKIEELRQHLWKWGFYTP
DNKHQKEPPFLWMGYELRPDKWTVQPIELP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006