Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9355 | 9355-30925 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | K20I, M36I, I62V, L63LP, I64V, T74TS |
| >9355-30925| codons 4-99 TLWQRPLVTIKIGGQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQVP VEICGHKAIGSVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, V75VM, L210W, T215Y | D67DEG, K219N | K101E, K103N, Y181C, G190A | K65KE, S68G, K73KM, K104KQ, K122E, E169D, R172RK, D177E, I178L, T200A, R211K, H235HR, V245E | N57NH |
| >9355-30925| codons 38-247 CTELEKEGKISKIGPENPYHTPVFAIKEKGGTKWRMLMDFRELNKRTQDFWEVQLGIPHP AGLEKNQSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILDPFKKQNPELVICQYMDDLYVASDLEIGQHRAKIEELRQHLWKWGFYTP DNKHQKEPPFLWMGYELRPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |