<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9309 9309-30918 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y   K101E, Y181C, G190A A98AG K43KQ, E44D, K64R, V118I, K122E, I135T, Q174E, V189I, T200A, E203K, Q207DE, H208Y, R211K, K223Q, V245M  
>9309-30918| codons 38-247
CTELEQDGKISKIGPENPYNTPVFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGLEKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKENPDIVICQYVDDLYIASDLEIGQHRAKIKELREYLWKWGFYTP
DKKHQQEPPFLWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54AS, V82C L24I, L33F, K43T L10I, I13V, I15V, K20R, E35D, M36I, N37D, R41K, I62V, L63P, I64V, A71V, T74S, I85V, I93L  
>9309-30918| codons 4-99
TLWQRPIVTVKVGGQLREALIDTGADDTVFEDIDLPGKWTPKIIGGIGGFSKVRQYDQVP
VEICGHKVIGSVLVGPTPCNIVGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006