Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9309 | 9309-30918 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54AS, V82C | L24I, L33F, K43T | L10I, I13V, I15V, K20R, E35D, M36I, N37D, R41K, I62V, L63P, I64V, A71V, T74S, I85V, I93L |
| >9309-30918| codons 4-99 TLWQRPIVTVKVGGQLREALIDTGADDTVFEDIDLPGKWTPKIIGGIGGFSKVRQYDQVP VEICGHKVIGSVLVGPTPCNIVGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K101E, Y181C, G190A | A98AG | K43KQ, E44D, K64R, V118I, K122E, I135T, Q174E, V189I, T200A, E203K, Q207DE, H208Y, R211K, K223Q, V245M |
| >9309-30918| codons 38-247 CTELEQDGKISKIGPENPYNTPVFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP GGLEKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKENPDIVICQYVDDLYIASDLEIGQHRAKIKELREYLWKWGFYTP DKKHQQEPPFLWMGYELHPDKWTVQPIMLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |