Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9179 | 9179-30916 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54L, I84V, L90M | L10I, K20R, E35D, M36I, N37ND, I62V, L63P, A71I, P79PS, I85V, Q92K, I93L |
| >9179-30916| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKLIGGIGGFLKVRQYDQVP IEICGHKIIGTVLVGSTPVNVVGRNLMTKLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, L210W, T215Y | V75S | Y181C | V108I | T39TA, S68G, V90I, K122E, I135T, M164MI, Q207N, R211K, H221Y |
| >9179-30916| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKISDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSITKILEPFRKQNPDIVICQYVDDLYVGSDLEIGQHRTKIEELRNHLWKWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |