Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9305 | 9305-30916 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L210W, T215Y | K103N, Y181C, G190A | K49KR, I135T, R211K, V245K |
| >9305-30916| codons 39-247 TEMEKEGKISRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPA GLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPA IFQSSMTKILEPFRKQNPDIVICQYMDDLYVASDLEIGQHRTKIEELRQHLWKWGFYTPD KKHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54AV, V82A, I84IV, L90M | Q58E | L10V, I15V, K20KR, M36MI, R41K, D60E, I62V, L63P, A71V, I93L |
| >9305-30916| codons 4-99 TLWQRPVVTIKVGGQLREALLDTGADDTVLEEINLPGKWKPKLIGGIGGFVKVREYEQVP IEICGHKVIGTVLVGPTPANVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |