Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9175 | 9175-30909 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K219N | Y181YC | A98G, F227L | T39A, E44D, V118I, I135T, I142T, S162C, Q174K, G196E, Q207D, H208Y, R211K, K223E, E224EK | E203KR |
| >9175-30909| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKKNPDIVICQYVDDLYVGSDLEIEQHRTKIRELRDYLWKWGFYTP DNKHQEKPPLLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82F, I84V, L90M | Q58E | L10I, I15V, K20R, E35D, M36I, L63P, A71V, I72V, V77I, I93L |
| >9175-30909| codons 4-99 TLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGRWKPKLIGGIGGFVKVREYDQIP IEICGHKVVGTVLIGPTPFNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |