<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9175 9175-30909 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82F, I84V, L90M Q58E L10I, I15V, K20R, E35D, M36I, L63P, A71V, I72V, V77I, I93L  
>9175-30909| codons 4-99
TLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGRWKPKLIGGIGGFVKVREYDQIP
IEICGHKVVGTVLIGPTPFNVIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N Y181YC A98G, F227L T39A, E44D, V118I, I135T, I142T, S162C, Q174K, G196E, Q207D, H208Y, R211K, K223E, E224EK E203KR
>9175-30909| codons 38-247
CAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRKKNPDIVICQYVDDLYVGSDLEIEQHRTKIRELRDYLWKWGFYTP
DNKHQEKPPLLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006