Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9171 | 9171-30904 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48A, I54V, V82A, L90LM | K43T, G73GS | L10I, K14R, I15IV, K20R, E35D, M36I, N37NS, R41RK, I62V, L63AP, A71V, I72IT, I93L |
| >9171-30904| codons 4-99 TLWQRPIVTIRVGGQLREALLDTGADDTVLEDISLPGKWTPKLIAGIGGFVKVRQYDQVP IEICGHKVTSTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K103KN | T39TA, K43E, W88C, D123E, Q145V, I178L, V179VI, G196E, E203D, V245E |
| >9171-30904| codons 38-247 CAELEEEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFCEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYVYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDLIIYQYVDDLYVGSDLEIEQHRTKIDELRQHLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |