<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9170 9170-30904 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, V75VM, M184V, T215FY K219E K103N, G190A   K49R, K102HQ, K122E, I135T, S162C, E169D, T200A, I202V, D218DE, L228H, P243H, V245E  
>9170-30904| codons 38-247
CTELEKEGKISRIGPENPYNTPVFAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLKQNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILDPFRKQNPDIVIYQYVDDLYVASDLEIGQHRAKVEELRQHLLRWGFYTP
EEKHQKEPPFHWMGYELHPDKWTVQHIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, I84V, L90M L33F, Q58E L10I, I13V, L19V, R41K, D60DE, L63P, A71V, I72V  
>9170-30904| codons 4-99
TLWQRPIVTVKIGGQVKEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGFVKVREYEQIP
IEICGHKVVGTVLVGPTPANVIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006