Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9170 | 9170-30904 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V, L90M | L33F, Q58E | L10I, I13V, L19V, R41K, D60DE, L63P, A71V, I72V |
| >9170-30904| codons 4-99 TLWQRPIVTVKIGGQVKEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGFVKVREYEQIP IEICGHKVVGTVLVGPTPANVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75VM, M184V, T215FY | K219E | K103N, G190A | K49R, K102HQ, K122E, I135T, S162C, E169D, T200A, I202V, D218DE, L228H, P243H, V245E |
| >9170-30904| codons 38-247 CTELEKEGKISRIGPENPYNTPVFAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKQNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILDPFRKQNPDIVIYQYVDDLYVASDLEIGQHRAKVEELRQHLLRWGFYTP EEKHQKEPPFHWMGYELHPDKWTVQHIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |