Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9330 | 9330-30929 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215F | K219Q | K101HPQ, Y181C, G190A | A98AG, V108VI | T39A, T69N, K103KR, R211K, D218E, L228H |
| >9330-30929| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHP GGLQKRKSVTILDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRTKIEELRQHLLKWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, L76V, V82A | L24I, L33F, K43T | L10I, T12K, I13V, R41K, K55KR, I62V, L63P, A71V |
| >9330-30929| codons 4-99 TLWQRPIVKVKIGGQLKEALIDTGADDTVFEEMNLPGKWTPKIIGGIGGFMRVRQYDQVP IEICGHKVIGTVVVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |