Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9238 | 9238-30915 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, M184V, L210W, T215F | K219Q | L100I, K103N | D121Y, K122E, I135T, D177E, H208Y, R211K, D218E, L228H, V245E |
| >9238-30915| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLYEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, N88D | I13V, K20R, L33M, E35D, M36I, K55R, I62V, L63P, A71T, I72E, Q92R, I93L, C95F | W6A |
| >9238-30915| codons 4-99 TLAQRPFVTVKIGGQLREALLDTGADDTVMEDINLPGRWKPKIIGGIGGFVRVRQYDQVP IEICGHKTEGTVLVGPTPVNVIGRDLMTRLGFTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |