Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9239 | 9239-30915 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, L210W, T215Y | V75A | L100I, K103N | T39A, K43E, E44A, V118I, K122E, I135T, S162N, D177G, G196E, H208Y | L228LFHY |
| >9239-30915| codons 38-247 CAELEEAGKISKIGPENPYNTPVFAIKKKNSDKWRKVADFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPGIVIYQYMDDLYVGSDLEIEQHRTKIEELRQYLWRWGFYTP DKKHQKEPPFYWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82F, I84V, L90M | L23LI, L33F, F53L, Q58E, G73GCS | L10I, T12N, E34Q, N37S, R41K, D60DE, I62V, L63P, A71AV, V77I | E21EV |
| >9239-30915| codons 4-99 TLWQRPIVNIKIGGQLKVAILDTGADDTVFQEMSLPGKWKPKIIGGIGGLIKVREYEQVP IEICGHKVISTVLIGPTPFNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |